Lignans from the fruits of Pandanus kaida Kurz. (Pandanaceae) and theirs a-Glucosidase inhibitory activities

Pandanus kaida Kurz is a arbsute, which combined with others medical plants for treatment of kidney stones, epididymitis and eyes diseases in Vietnamese traditional medicines. However, little scientific publication available this plant. The aim study to isolate chemical constituents the fruits K. (Pandaceae) order provide more information add database Vietnam. Results showed five compounds including: epi-pinoresinol (1), (+)-pinoresinol (2), (+)-syringaresinol (3), (+)-medioresinol(4), (+)-isolariciresinol (5), have been isolated from (Pandanaceae), collected Duc Hoa District, Long An Province, Extraction was carried out by heating under reflux liquid-liquid extraction organic solvents increasing polarity yeild corresponding soluble fractions, then, using chromatography methods such as column on silica gel, preparative TLC eluting different obtaining compounds. Their structures were elucidated based NMR spectroscopic analysis, HR-ESI-MS, specific optical rotation comparison literature. Three lignans (+)-medioresinol (4) potent a-glucosidase inhibitory activity.